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Successful IVF with donor eggs at the Advanced Fertility Center of Chicago – egg donation clinic with proven egg donors Google

March 27th, 2013

Egg donation (oocyte donation or ovum donation) is an effective treatment for infertility except in women with a severe uterine problem, such as extensive intrauterine adhesions.

Success rates with egg donation are high, particularly compared to pregnancy rates in women with poor egg quality and quantity.

Donor egg IVF is generally used in women with significantly diminished egg quantity and quality (poor ovarian reserve). This includes women with:

  • Premature ovarian failure (early menopause)
  • Very poor egg quality
  • Poor response to ovarian stimulation
  • High day 3 follicle stimulating hormone (FSH) levels
  • Very low antral follicle counts on ultrasound
  • Advanced female age, such as over age 40
Our 2011 success rate with donor eggs

 

80%
Live birth rate
Per embryo transfer
2011 national average success rate with donor eggs 54.9%
Live birth rate
Per embryo transfer
A comparison of clinic success rates may not be meaningful because patient medical characteristics, treatment approaches and entrance criteria for ART may vary from clinic to clinic.
  • Know the success rates at your clinic before you do treatment anywhere with donor eggs
  • See any clinic’s IVF and donor egg success rates by following links to SART or CDC

How are the egg donation procedures performed and how is the timing of IVF with donor eggs done in donor egg IVF cycles?

  1. An appropriate egg donor is chosen by the infertile couple and thoroughly screened for infectious diseases and genetically transmissible conditions. Donors are generally given money for going through the treatment. Donors can be known or anonymous to the recipient couple. Our clinic does most cases using one of our anonymous donors.
  2. Consents are signed by all parties.
  3. The donor is stimulated with injected medications to develop multiple egg development. This allows us to perform in vitro fertilization with her eggs and the sperm of the infertile woman’s male partner.
  4. Details about the subcutaneous injectable medications that are used for IVF
  5. Sample calendar of a “typical” egg donation cycle that shows the days of medications, procedures, etc.
  6. The infertile woman (recipient) is placed on medications:
    • Lupron suppresses her own menstrual cycle
    • Estrogen patches or pills to stimulate development of a receptive uterine lining

Making a receptive uterine lining

With egg donation, a lining thickness of 8mm or more is desired to maximize success rates. Usually it is not difficult to get a good lining thickness for egg donation, but sometimes we need a modified estrogen protocol to get sufficient thickness.

uterine lining ultrasound Successful IVF with donor eggs at the Advanced Fertility Center of Chicago   egg donation clinic with proven egg donors

Ultrasound images of a uterus with a normal endometrial lining that is 11.2 mm thick
The endometrium is the landing pad - embryo implantation zone

uterine lining ultrasound draw Successful IVF with donor eggs at the Advanced Fertility Center of Chicago   egg donation clinic with proven egg donors

Same image showing outer contour of uterus outlined red and “triple stripe” lining in green

Egg donation process

When the donor’s follicles are mature, an egg aspiration procedure is performed to remove the eggs from her ovaries. The eggs are then fertilized in the laboratory with the sperm of the infertile woman’s male partner.

 

The eggs are used fresh and are not frozen for later use. In the future, frozen donor eggs might be used routinely for egg donation. However, current egg freezing technology does not allow the same high success rates that are seen when using fresh eggs. However, freezing of leftover fertilized embryos is now routine, and success rates using frozen embryos are excellent.

The chart below shows data from all of our donor egg cycles in 2009 and the first half of 2010. Shown are the average number of eggs, mature eggs, fertilized eggs, 8 cell embryos on day 3 and blastocyst embryos on day 5. Also shown are the average number of embryos transferred, frozen, and number of babies born (from transfer of fresh embryos).

Even using donor eggs there is drop off as embryos develop in the lab. But there are still enough good ones to make lots of babies.

egg donation number eggs embryos babies Successful IVF with donor eggs at the Advanced Fertility Center of Chicago   egg donation clinic with proven egg donors

 

Timing of donor egg fertilization with the recipient’s uterine receptivity

Getting the proper timing in IVF with donor eggs between the uterine lining in the recipient and the developing embryos is critical for a successful donor egg IVF cycle.

This is accomplished by carefully controlling the start time of the drug (hormone) progesterone (also called P4) in the recipient woman. Not all egg donation clinics start progesterone at exactly the same time. Our protocol starts P4 on the evening before the donor’s egg retrieval procedure.

The embryos develop in the laboratory for 3 to 5 days. Then, an embryo transfer procedure is done which places the embryos carefully in the recipient woman’s uterus where they will hopefully implant and develop on to a successful birth.

Sample calendar for a donor egg treatment cycle

Availability of egg donors

We currently have ovum donors available that are interested in donating eggs to infertile couples. We do not currently have a waiting list for couples needing egg donors.

Success rates with donor eggs

Success rates for IVF using donor eggs varies considerably depending on several variables including the age of the donor, her egg quantity and quality, the number of embryos transferred, the quality of the recipient’s uterine lining, and the particular IVF center handling the case. Pregnancy rates are generally as high, or higher than that seen with the use of eggs from very young (under 32) infertile women.

Thegraph below is from a recent ART Success Rates report published by the CDC (Centers for Disease Control and Prevention) – a US Government agency.

  • This report was generated from national data from hundreds of clinics and over 100,000 IVF cycles
  • It is not data from our center (although we are included in it)
  • It shows the rate of live births per embryo transfer procedure by the age of the recipient of the embryos
  • The green line shows data using the infertile woman’s own eggs, while the dark blue line shows data from donor egg cycles

This chart illustrates the decline in live birth rates by female age beginning at about age 28. The rate of decline becomes somewhat greater starting at about age 38. In vitro fertilization with own eggs rarely results in a live birth beyond age 43.

An important point is that there is basically no decline in live birth rates by age of recipient when donor eggs are being used (top line doesn’t drop with age).

  • The age of the eggs is very important, but the age of the uterus is not important

 

The national summary (as well as clinic specific results) of IVF cycles done in the years 1997-2010 are posted on the CDC’s website. Links to CDC and SART reports are on our site.

 

  • Some programs, including ours, have delivery rates averaging over 70% per embryo transfer procedure for egg donation cases
  • The national donor egg success rate is currently about 56% per transfer procedure

 

What is the history of IVF using donor eggs?

 

The process of human egg donation began in 1982 with the first live birth success. Currently, over 16,000 egg donation procedures are done annually in the US


Infertility Google

March 27th, 2013

82637446 INFERTILITY 342x198 InfertilityInfertility is when a couple cannot conceive (get pregnant) despite having regular unprotected sex.

Around one in six couples may have difficulty conceiving. This is approximately 3.5 million people in the UK.

About 85% of couples will conceive naturally within one year if they have regular unprotected sex. However, the chances of becoming pregnant are much lower in older women.

For every 100 couples trying to conceive naturally:

  • 20 will conceive within one month
  • 70 will conceive within six months
  • 85 will conceive within one year
  • 90 will conceive within 18 months
  • 95 will conceive within two years

For couples who have been trying to conceive for more than three years without success, the likelihood of pregnancy occurring within the next year is 25% or less.

Deciding to seek help

Some women get pregnant quickly but for others it can take longer. It is a good idea for a couple to visit their GP if they have not conceived after one year of trying.

Women over the age of 36, and anyone who is already aware they may have fertility problems, should see their GP sooner. The GP can check for common causes of fertility problems, and suggest treatments that could help.

A couple will only be diagnosed as being infertile if they have not managed to have a baby after one year of trying. There are two types of infertility:

  • primary infertility, where someone who has never conceived a child in the past has difficulty conceiving
  • secondary infertility, where a person has had one or more pregnancies in the past, but is having difficulty conceiving again

Read more information about how infertility is diagnosed.

What causes infertility?

There are many potential causes of infertility, and fertility problems can affect either the man or the woman. However, it is not always possible to identify the cause.

Common causes of infertility in women include lack of regular ovulation (the monthly release of an egg), blockage of the fallopian tubes and endometriosis, although in 25-30% of cases the cause is unexplained. In men, the most common cause is poor quality of semen (the fluid containing sperm that is ejaculated during sex).

For some people, leading a healthy lifestyle and staying up to date with regular health checks and tests may help toprevent infertility.

What treatment is available?

Types of fertility treatment available include:

  • medical treatment for lack of regular ovulation
  • surgical procedures, such as treatment for endometriosis
  • assisted conception, which may be intrauterine insemination (IUI) or in-vitro fertilisation (IVF)

The treatment offered will depend on what is causing your fertility problems and what is available from your Primary Care Trust.

You may wish to consider private treatment. This can be expensive and there is no guarantee it will be successful.

It is important to choose a private clinic carefully. You can ask your GP for advice, and you should make sure you choose a clinic that is licensed by the Human Fertilisation and Embryology Authority (HFEA).

Read more information about how infertility is treated.

Some types of infertility treatment can cause complications including:

  • side effects of medication
  • increased risk of ectopic pregnancy
  • multiple pregnancy
  • stress

Read more information about complications associated with infertility treatments.

Fertility: the facts Google

March 27th, 2013

10015330 FACTS 377x171 Fertility: the factsConception is when a woman’s egg is fertilised by a man’s sperm, and then implants itself into the woman’s womb. Most couples don’t have a problem getting pregnant.

Watch a video about the menstrual cycle

For most couples, regular unprotected sex is all it takes to conceive a child.

If you’re trying for a baby or thinking of doing so in the future, knowing the basic facts about fertility can be helpful.

The monthly cycle

Every month, hormonal changes in a woman’s body cause the ovaries to release a single egg. This egg passes into the fallopian tubes, which link the ovaries to the uterus (womb).

At the same time, the lining of the womb thickens. This is to prepare it for the possibility of receiving a fertilised egg.

If fertilisation does not occur, the womb lining will break down and will be shed through the vagina. This is a woman’s period. The period is made up of the womb lining and a small amount of blood.

Women of childbearing age have a period approximately every 28 days, although the length of the cycle can vary and between 24 and 35 days is common.

If a woman has unprotected sex with a man around the time of her egg being released, sperm from her partner may fertilise her egg while it is in the fallopian tube. The fertilised egg will then travel to the womb and become embedded in its lining, where it will start to grow.

Find out more about periods and the menstrual cycle.

How conception occurs

An egg can be fertilised by sperm during the 12 to 24 hours after it has been released from the ovaries.

Sperm can survive in the fallopian tubes for up to seven days, so fertilisation can occur even if sperm entered the fallopian tubes before an egg was released.

During conception, a single sperm from a man penetrates the egg of a woman. The sperm carries the father’s genes, while the mother’s genes are contained in the egg. Once the egg has been fertilised by a single sperm, no more sperm can enter.

The fertilised egg, called a zygote, continues to move down the fallopian tubes, until it reaches the womb. Here, it will implant itself into the lining of the womb (about 6-10 days after ovulation), where it begins to grow.

Until eight weeks after conception, the implanted zygote is called an embryo. After this it is called a foetus.

For most women, the first sign that they are pregnant is a missed period. A few days after that missed period, a urine test can confirm the pregnancy.

Urine tests for pregnancy are available through your GP or family planning clinic. You can buy a test to do at home at your local pharmacy or supermarket.

If you think you may be experiencing fertility problems, see

Artificial insemination Google

March 27th, 2013

56947430 artificial insemination 342x198 Artificial insemination Artificial insemination is a treatment for infertility, when a couple cannot conceive a baby. It involves directly inserting sperm into a woman’s womb.

When is artificial insemination used?

Artificial insemination can help a couple conceive if:

  • there is a problem with the man’s sperm or he has erectile dysfunction or premature ejaculation
  • there is no obvious reason why the couple cannot conceive (unexplained infertility)
  • the woman has ovulation problems or mildendometriosis, when cells usually found in the lining of the womb grow in other parts of the reproductive system

Women without a male partner, such as women in same-sex partnerships, have also used artificial insemination to become pregnant.

Read more information about why artificial insemination is used.

Intrauterine insemination (IUI)

Intrauterine insemination (IUI) is the technique used for artificial insemination, and it has a good record of success.

Figures from the Human Fertilisation and Embryology Authority (HFEA) in 2009 found that IUI has a success rate of around 15% for each cycle of treatment. However, a number of factors can affect this.

Read more about the results of artificial insemination.

There are some risks associated with IUI when used in combination with fertility medication. This includes a higher chance of multiple pregnancy and a small but potentially serious chance of causing ovarian hyperstimulation syndrome (OHSS).

Read more about the risks of artificial insemination.

In IUI, a man provides a sample of sperm, which is then “washed” and filtered using special techniques. This ensures that only the highest-quality sperm is used for the procedure.

During the procedure, the concentrated sperm is passed directly into the woman’s womb through a thin tube called a catheter.

Read more about how artificial insemination is performed.

Sperm donation

If the male partner cannot produce healthy sperm, frozen sperm from a donor can be used.

Some couples obtain donated sperm from someone they know. However, in most cases, sperm is obtained from an unknown donor.

Donor anonymity

In the past, sperm donors remained anonymous from the parents and the child produced by the donated sperm. However, in 2005, the law regarding donor anonymity changed.

Anyone born from donated sperm after April 1 2005 can apply to HFEA to obtain information about the identity of the donor, once they have reached 18 years of age.

The HFEA is the independent regulator for all fertility clinics in the UK.

Artificial insemination on the NHS

The National Institute for Health and Clinical Excellence (NICE) recommends that up to six cycles of IUI treatment on the NHS may be offered if:

  • you are unable (or would find it very difficult) to have vaginal intercourse, for example because of a physical disability
  • you have a condition (such as a viral infection that can be sexually transmitted) that means you need specific help to conceive
  • you are in same-sex relationship

Previously, IUI treatment on the NHS was offered if:

  • a man has mild fertility problems
  • a woman has mild endometriosis
  • a couple has unexplained fertility problems

However, new guidelines released in 2013 state that IUI should no longer be offered in these circumstances. Instead, you should be advised to keep trying to conceive through regular unprotected sexual intercourse for a total of 2 years. After this time you may be offered in vitro fertilisation (IVF).

Read more about when artificial insemination is used.

The availability of fertility treatment on the NHS varies throughout the UK. In some areas, the waiting list for treatment can be very long. The criteria that must be met to be eligible for treatment can also vary.

IUI is also available from private fertility clinics. Costs vary from £500 to £1,000 for each cycle of treatment.

Each cycle of IUI is timed to coincide with the woman’s natural reproductive cycle, so you will only be able to receive one cycle of IUI treatment a month

In Vitro Fertilization Google

March 25th, 2013

features IVF 1 In Vitro FertilizationNowadays there are big problems in many families  around the world. This belongs to Fertilization. In Vitro Fertilization is one of the great way to solve this problems and make partner happy.

Many thinks that it is not possible, but today’s success rates tell another.

There are many In Vitro Fertilization Clinics all over the world and they have not same prices. Of course there are good, the best and the worst ones but we and this site will help you to choose the best of the best.

In Vitro Fertilization, in a nutshell IVF, is best treatment infertility when other methods of reproductive technology have failed. It’s the process when egg cells are fertilized by sperm outside the body.

Robert G. Edwards was the doctor who developed treatment. He received Noble Prize in 2010.

In Vitro Fertilization (Ivf) Google

March 25th, 2013

ivf 1 In Vitro Fertilization (Ivf)Infertility means that couple will not have baby without some technical methods of fertilization. One of popular method is In Vitro Fertilization IVF. There are also Intracytoplasmic sperm injection ICSI and similar ones.  These are new advanced technologies for women to became pregnant.

In Vitro Fertilization IVF was used in 1981 and since this more than 250000 babies have been born using it. You will see many times the term “Test tube baby” which refers babies born with this way. IVF also is used when man hassperm problems, like, low sperm count and etc.

Nowadays In Vitro Fertilization IVF is recognized as worldwide established treatment for infertility.

 

ivf In Vitro Fertilization (Ivf) ivf cycle1 In Vitro Fertilization (Ivf)

IVF success rates rise with 40% with new IVF method Google

March 23rd, 2013

Gender Selection1 300x187 IVF success rates rise with 40% with new IVF methodDoctors at Newcastle University developed new technology which rose IVF success rates with 40%. They made this by creating laboratories which mimic conditions found inside the womb.

This Technology promises that financial costs will reduce for this treatment and this is another great news for women. Because of IVF is not fail-safe, it could be cost much more than you expected.

In Vitro Fertilization has some steps that should be done. The embryo should be grown in an incubator before placed into the womb. But doctors have to check Embryo under the microscope, and here is the problem. This can make air and temperature change for Embryo, which however can be potential harmful for process.

So Doctors at Newcastle developed some “lab in box” which has in-built microscopes in the incubators. This method solves many problems.

Now Pregnancy rates in the clinic where this system already have installed rose with 40%.

Labs in the Netherlands, Canada and Thailand have all installed systems based on the Newcastle design.

You should know about 4 foods for increasing Fertility Google

March 23rd, 2013

pregnant woman carrying a basket of vegetables 300x200 You should know about 4 foods for increasing FertilityWhen woman is pregnant, it is an exciting time for her. So there are many ways to increase chances of getting pregnant. The good nutrition is one of the best way for this. We tried to give information about these foods.

1. At first you need to eat Fresh Fruit and Vegetables

Especially citrus fruits, strawberries, mushrooms and spinach, can increase fertility. Adequate folic acid is also very important in a pre-pregnancy diet to decrease the risk of birth defects. It is important to get B and C vitamins. His help can make also guy. He can eat apples which  raises the sperm count in men. As Tomato, avocado, pink grapefruit and watermelon increases both sperm motility and count. at last, bananas are very useful for making sperm more productive.

2. Milk products

You should drink whole milk. This helps with ovulation. Also Ice cream is good option.

3. Plant Protein vs Animal Protein

Protein from plants is more good for becoming pregnant than animal protein. You can replace meat with tofu, soy and etc when you are trying become pregnant.

4. Zinc-rich foods like crab…

Try to get Zinc-rich foods. It is beneficial as for men, as women. Crab, nuts, bean seeds and oysters are very useful.

IVF in Eastern Europe – Five Things You Should Know Google

March 23rd, 2013

UKNews200220130348401 1 IVF in Eastern Europe   Five Things You Should KnowIVF in  Eastern Europe – Five  Things You Should Know 

Treatment in Eastern Europe is cheaper, but…

….this is partly because the fertility drugs are cheaper in these countries. You’ll probably know that everything’s cheaper in Eastern Europe – cheap food, cheap vodka, cheap hotel insurance. You also need to be aware that you will received a different service in Eastern Europe. Check to find out what kind of aftercare is included in the package you opt for. Find out all you can about the clinic you have chosen before making a decision, and be mindful that standards of regulation differ from country to country. Discuss with your GP if you are in doubt. On the plus side almost all the care staff you will encounter will speak English, and the doctors there keep up with all the latest developments in IVF treatments.

Treatment in Eastern Europe is more successful, but…

…be aware that this is partly because they use different treatment techniques to those of the US and UK. Clinics implant more embryos per cycle, which means the success rates seem higher. This is fine, but be mindful that this could mean more chance of a multiple birth, with the attendant increase in the chance of birth defects. This said, the occurrence of multiple births is dropping progressively as treatments improve.

Treatment for IVF is getting harder to obtain in the UK…

The UK Government limits IVF treatment to one cycle per couple, where the woman is between 23 and 39, a cause of infertility has been diagnosed and after they have been trying to have a baby naturally for two years. In some areas of the country it is even harder to secure treatment. For many this only leaves the option of private treatment open to them.

Fertility Tourism is increasing…

It is good news is that Fertility Tourism to Eastern Europe is increasing. The trend could increase further too. Some 4% of medical tourists get fertility treatment, and this number is likely to rise as financial pressures limit the number of IVF rounds couples are entitled to on the NHS. An new EU directive on cross-border healthcare, which was passed in January 2011, comes into force in 2013 which will make things easier too. The directive establishes patients’ rights to be reimbursed for treatment they receive in other EU countries, and could lead to more West Europeans travelling to Eastern Europe for care. As with anything which is in demand, if there is a good customer base it’s easier to find out what you will be signing up for. Make full use of forums to find out about other people’s experiences and make sure you find out all you can about what to expect when you arrive. Word of mouth and recommendation is invaluable, so don’t neglect to ask all you can of your friends in the forum.

It might be tough being abroad…

Many women overlook this side of the Fertility Abroad deal, but a bit of planning can make it much easier. You may need to be away from home for between three to five weeks during treatment. Some women find this very difficult and stressful. In a country where you don’t speak the language it can be a really lonely, isolating experience.  To you’re your time away from your loved ones more bearable make sure you find out as much as you can about the area you will be staying in before you set off. Is there an ExPat community you could meet up with, for some instant socialising and interest? Get onto the internet and find a forum for people who speak your language and will be local.  Why not be open about why you’re visiting? Other women can be very supportive and might be happy to share your joy or support you should things not go to plan. You could also ask good friends to come out and visit you in your chosen country and plan some good days out for when they arrive. You could write a diary or blog to keep your friends up to date with your progress – it might be useful for other women to see how your trip has gone. A video diary is another idea. Anything to keep you engaged during the treatment will make the time pass more quickly.

The Message Is Clear

Fertility treatment is a difficult path to choose, whether at home or abroad. The message about travelling abroad is very clear however. Yes there are advantages, but do your homework first, and make sure you know exactly what you’re getting into.

Egg Donation Google

March 23rd, 2013

Egg Donation

insemination 100326 02 Egg DonationThe first Egg donation was made in July 1983.  It was huge step in IVF.

Egg Donation is the procedure  when using another woman’s eggs for conception by a recipient couple. Egg Donor should be women with age of 21-35. She also must be in excellent health, as in physical as in mental health.  Before Egg donation, women must be full understanding of the process…

There are many clinics for this, and if you really want to be Egg Donor, you can contact them. At this moment privacy is secured very strong. Clinics have their Lists of woman who are ready for Egg donation, so when couple searches women for this they are offering various ways.

Egg donation became needed more and more. Infertility Couples want Egg donation, because of female partner, who cannot have genetic children because she may not have eggs that can generate a viable pregnancy.

442607a i1.0 Egg DonationEgg donation has no effect on ability to have children in future… Payment for Egg donor is various in various countries, but average number for this is around $5,000-$7,000.

If you want to know that will you have scar or not, answer is sample, Egg retrieval usually done through the vagina. It is done while you are sleep.

Last factor that i will consider your attention in this post is about question that How can you be sure the parents won’t give you back this baby some day? Yes its another problem, and you must see Law and contract too good for answer this question.